Pre-implantation Genetic Screening (PGS)
What Is PGS?
Pre-implantation Genetic Screening, now commonly called PGT-A, examines embryos for the correct number of chromosomes. Embryos with abnormal chromosome numbers are a leading cause of failed implantation and miscarriage, particularly as a woman gets older.
Who May Consider It?
Advanced Maternal Age
Women of advanced maternal age.
Recurrent Miscarriage
Couples with recurrent miscarriage.
Implantation Failure
Repeated implantation failure after good-quality embryo transfers.
Reducing Risk
Couples who want to reduce the chance of chromosomal problems.
Your specialist will discuss whether screening is right for you.
How It Is Done
Cell Sampling
During IVF, a small sample of cells is taken from each blastocyst and tested.
Freezing
Embryos are usually frozen while results are awaited.
Later Transfer
A normal embryo is transferred in a later cycle.
What the Evidence Says
Research shows that PGT-A may shorten time to pregnancy and reduce miscarriage in some groups, but it does not increase the number of embryos and benefits are not equal for every patient. Some embryos labelled abnormal may be mosaic. Your specialist will discuss whether screening is right for you.
How We Help
Curis Global arranges consultation with fertility specialists, explains the cost and the process and handles your travel and stay.
Frequently Asked Questions
Is PGS the same as PGD?
No. PGS looks at chromosome numbers generally, while PGD tests for a known inherited condition.
Does it guarantee a baby?
No. It improves embryo selection, but pregnancy is never guaranteed.