Intra Cytoplasmic Sperm Injection (ICSI)
What Is ICSI?
Intra Cytoplasmic Sperm Injection is a laboratory technique in which a single healthy sperm is injected directly into a mature egg. The fertilised egg then develops as an embryo, which is transferred to the uterus just as in standard IVF.
When Is ICSI Recommended?
ICSI is recommended in cases such as:
Low Sperm Count
Very low sperm count or poor motility.
Abnormal Sperm Shape
Abnormal sperm shape.
Failed Fertilisation
Previous failed fertilisation with standard IVF.
Surgically Retrieved Sperm
Use of surgically retrieved sperm (for example from the testis).
Frozen Sperm
Frozen sperm of limited quality.
ICSI is not automatically better for everyone. For couples without male-factor problems, standard IVF may work equally well.
The Process
Stimulation and Egg Retrieval
The woman goes through stimulation and egg retrieval as in IVF.
Sperm Selection
On the same day, an embryologist selects sperm under a powerful microscope.
Injection
The embryologist injects one sperm into each mature egg.
Fertilisation Check
Fertilisation is checked the next day and embryos are monitored before transfer.
Male Evaluation
A semen analysis, hormone tests and, where indicated, genetic tests help find the cause. Some men benefit from lifestyle changes or medical treatment alongside ICSI. If no sperm are present in the ejaculate, a urologist may retrieve sperm surgically.
Our Support
Curis Global connects you with clinics that have skilled embryologists, arranges coordinated visits for both partners and helps plan travel timing around the cycle.
Frequently Asked Questions
Does ICSI cause birth defects?
Studies show that most children are healthy, though a small increased risk may relate to underlying male infertility. Genetic counselling can help.
Is ICSI painful?
The laboratory step is not felt. Egg retrieval is done under sedation.